Almost all of England will go into tiers two and three when the lockdown ends on 2 December.
Some backbench MPs say the new restrictions could lead to "utter devastation" for local economies.
Some trial volunteers were given shots half the planned strength, so how does that affect the results?
People travelling to the UK from the two countries will need to quarantine from Saturday.
Scotland's first minister says a referendum should be held "in the earlier part" of the next Scottish Parliament.
Rollout will start with care home residents and staff, health and social care workers and those over 80.
Officers are granted extra powers to search vehicles this weekend in Cardiff to stop Covid breaches.